PharmaCenter Bonn, Pharmaceutical Institute, Pharmaceutical Chemistry I, University of Bonn, Bonn, Germany . 3PharmaCenter Bonn, Pharmaceutical Institute, Pharmaceutical & Medicinal Chemistry, University of Bonn, Bonn, Germany. fluorescent ligands and ESR probes, BioPharma-Neuroallianz (Steering Committee Med. Author information: ... D-53121 Bonn, Germany. christa.mueller@uni-bonn.de. Prof. Dr. Michael Gütschow Pharmazeutisches Institut Universität Bonn Tel. Phone: +49 (0) 228 73 2301. nat. An der Immenburg 4. D-53127 Bonn Möller, Carolin: Institute of Pharmacology and Toxicology Research group Prof. Dr. Alexander Pfeifer Biomedical Center I Venusberg-Campus 1 D-53127 Bonn: Perri, Filomena: Pharmaceutical Institute Pharmaceutical/Medicinal Chemistry Research group Prof. Dr. Christa E. Müller An der Immenburg 4 D-53121 Bonn Pütz, Laura : 0228/73-2301. Heterotrimeric G protein subunits Gαq and Gα11 are inhibited by two cyclic depsipeptides, FR900359 (FR) and YM-254890 (YM), both of which are being used widely to implicate Gq/11 proteins in the regulation of diverse biological processes. An emerging major research question therefore is whether the … Ectonucleotidase inhibitors. Abbotabad, Pakistan, Alzheimer Forschung Initiative: A2A Receptor Modulation for the Therapy of | Zuständige Aufsichtsbehörde: Ministerium für Wissenschaft und Forschung des Landes Nordrhein-Westfalen, Völklinger Straße … The drug candidates are able to switch off the the key enzyme of the virus, the so-called main protease. Christa E. Müller. visit: www.purineclub.uni-bonn.de. Dr Christa Lankes Institute of Crop Science and Resource Conservation Horticultural Science Auf dem Hügel 6 D-53121 Bonn. Bonn, Germany July 22-25, 2011 The presidents of the Purine Clubs: Herbert Zimmermann, Germany. Prof. Dr. Christa Müller. Drug Sciences (BIGS-DrugS), Project leader, DFG-Graduiertenkolleg GRK1873 (PI of one Research interests. Medical Chemistry, Chemical Biology and Molecular Pharmacology of Purinergic receptors (adenosine, P2Y, P2X, adenine receptors) G-protein-coupled receptors / orphan GPCRs. Marx D(1)(2), Schnakenburg G(3), Grimme S(4), Müller CE(5)(6). Prof. Dr. Christa E. Müller, PharmaCenter Bonn, Pharmaceutical Institute, Pharmaceutical Chemistry I, University of Bonn, An der Immenburg 4, D‐53121 Bonn, Germany. "The main protease is an extremely promising starting point for coronavirus drug research," says Prof. Dr. Christa E. Müller of the Pharmaceutical Institute at the University of Bonn. The opioids used today to treat severe pain can be addictive and sometimes have life-threatening side effects. Prof. Dr. Christa Elisabeth Müller Head of Department of Pharmaceutical & Medicinal Chemistry, Pharmaceutical Institute Curriculum vitae 1: Prof. Dr. Christa E. Müller. Mailing List Please feel free to sign up to the mailing list to receive updates as they become available. A2 Organic phase (extracellular matrix, osteocyte, blood vessel) preservation in dinosaur bone: Chemical composition and hypotheses — Principal Investigators P. Martin Sander and Christa Müller, Ph.D. students Kayleigh Weyand and Mariam Tahoun project, Co-PI of one project), Collaboration with biotech/pharma companies, DAAD Project International Master of Science in Drug Research with COMSATS University, Universität Bonn / University of Bonn Pharma-Zentrum Bonn Brühler Str. Auf LinkedIn können Sie sich das vollständige Profil ansehen und mehr über die Kontakte von Christa Müller und Jobs bei ähnlichen Unternehmen erfahren. The study is based on laboratory experiments. | Jan 05, 2017, Hinweise Datenerhebung und Datenverarbeitung, BIGS DrugS researcher discover SARS-CoV-2 inhibitors, BIGS DrugS PhD student Katharina Dauer is awarded, Blood breakdown product affects important enzyme, Argelander Grants for BIGS Drugs PhD students researching Covid 19 pandemic, Medical Chemistry, Chemical Biology and Molecular The results facilitate the development of new active substances. Markus Gabriel. christa.mueller@uni-bonn.de. Tel: +49 (0)228-73 5150 Fax: +49 (0)228-73 5764 E-Mail: lances(at)uni-bonn.de Die Auswahl der Bewerber erfolgt nach den Kriterien. 6-Amino-5-amidouracil derivatives … The junior scientist Dr. Thanigaimail Pillaiyar (research group Prof. Christa E. Müller) is a leading expert in the field of corona viruses.His promising work focuses on the Main Protease (M pro) of SARS-CoV-2, which is essential for viral replication. Prof. Dr. Christa E. Müller Head of the Pharmaceutical Chemistry I, Pharmaceutical Institute . jlorek 7 53119 Bonn. Caffeine, an adenosine receptor antagonist, blocks various receptors in the brain which are activated by adenosine. Pharmaceutical Institute Pharmaceutical Chemistry I An der Immenburg 4 53121 Bonn, Germany . Technologies / resources. Die Arzneimittelkandidaten scheinen geeignet, das Schlüsselenzym des Virus, die sogenannte Hauptprotease auszuschalten. +49 (0)228-732317 E-mail: guetschow@uni-bonn.de. Christa MÜLLER | Cited by 1,655 | of University of Bonn, Bonn (Uni Bonn) | Read 150 publications | Contact Christa MÜLLER Connect with us. D-53121 Bonn . E-Mail: alexander.pfeifer[at]uni-bonn.de Prof. Dr. Christa E. Müller Speaker Pharmaceutical Institute, An der Immenburg 4, 53121 Bonn Phone (assistant Prof. Dr. Müller) +49 228 - 73-3890 E-Mail: christa.mueller[at]uni-bonn.de Dorothee Müssemeier Coordinator. one project on Gq-proteins), Bonn International Graduate Research School of Team from Bonn University. Dominik THIMM | Cited by 281 | of University of Bonn, Bonn (Uni Bonn) | Read 22 publications | Contact Dominik THIMM Pharmazeutische & Medizinische Chemie. Email: s6saleee@uni-bonn.de ; ; Tel: +49 228 73 2480. Universität Bonn / University of Bonn Pharma-Zentrum Bonn Seine vielversprechende Forschung setzt an der für die Replikation (Vermehrung) der essentiellen Protease M pro von SARS-CoV-2-Virus an. AG Müller Prof. Dr. rer. ... Christine Müller. Curr. … 1PharmaCenter Bonn, Pharmaceutical Institute, Pharmaceutical & Medicinal Chemistry, University of Bonn, Bonn, Germany. Medicinal chemistry and molecular pharmacology of purine binding membrane proteins (purine receptors, ectonucleotidases); lipid … Die 2018 Preisverleiung fand wahrend des XXV EFMC International Symposiums on Medicinal Chemistry ( EFMC-ISMC 2018 ) , September 2-6, 2018 in Ljubljana, Slovenia statt . Ein Forschungsteam von Pharmazeuten der Universität Bonn hat zwei Wirkstoff-Familien entdeckt, die die Vermehrung des Coronavirus SARS-CoV-2 blockieren können. 8-Arylethynylxanthine derivatives are potent, selective adenosine A2A receptor antagonists, which represent (potential) therapeutics for Parkinson's disease, Alzheimer's dementia, and the immunotherapy of cancer. Im Rahmen eines deutsch-französischen Forschungsprojekts konnte ein Team um Prof. Dr. Christa E. Müller von der Universität Bonn und Dr. David Blum von der Universität Lille 2/Inserm nun erstmals zeigen, dass sich Koffein positiv auf Tau-Ablagerungen bei der Alzheimer-Krankheit auswirkt. Uni Bonn Der Nachwuchswissenschaftler Dr. Thanigaimalai Pillaiyar (AK Prof. Dr. Christa E. Müller) forscht ebenfalls an neuen Wirkstoffen gegen Coronaviren. Second Circular – Registration form. Tel. Prof. Dr. Christa E. Müller. phone international: +49-228-73-2301. Andreas Brunschweiger, Christa E. Müller; P2 Receptors activated by uracil nucleotides – an update. Development of screening assays. Christa E Müller 1 , Younis Baqi 2 , Vigneshwaran Namasivayam 3 Affiliations 1 PharmaCenter Bonn, Pharmaceutical Institute, Pharmaceutical & Medicinal Chemistry, University of Bonn, Bonn, Germany. J. Based on the results of Prof. Dr. Christa Müller from the University of Bonn, Dr. David Blum and their team, a new class of drugs may now be developed for the treatment of Alzheimer’s disease. benders : +49 (0) 228 / 73-2301 Prof. Christa E. Müller is the new Deputy Rector for Planning and Finance, University of Bonn The Senate of the University of Bonn has approved the election of Prof. Christa E. Müller as the new Deputy Rector for Planning and Finance starting from the 2001/2002 winter semester. Prof. Dr. Christa Müller. The viral main protease then cuts this protein chain into smaller pieces, from which the new virus particles are formed. Website. To this end, the researchers target so-called photo-activatable agents. Für die Entwicklung von Medikamenten sind noch aufwändige … Christa E. Müller, Uli Geis, Jo Hipp, Ulrike Schobert, Wolfram Frobenius, Maciej Pawłowski, Fumio Suzuki, Jesús Sandoval-Ramírez; Synthesis and structure-activity relationships of DMPX (3,7-dimethyl-1-propargyl‑xanthine) derivatives, A 2A-selective adenosine receptor antagonists. Search for more papers by this author. Synthesis of drug molecules (small molecules) … 2Department of Chemistry, Sultan Qaboos University, Muscat, Oman. | Jul 19, 2009, PZB members develop SARS-CoV-2 inhibitors, Argelander grants for corona research for BIGS DrugS PhD studens, The Pharma Center is a member of the Academic DRUG DISCOVERY Consortium, NRW International Research School Chemical Biology. mammalian cells, insect cells and yeast), mutagenesis studies, Development of radioligands (including PET-ligands), General Management and Coordination. Group Leader. z.H. Dr. Dominik Thimm. Frau Prof. Christa Müller, Universität Bonn wurde mit dem renommierten Nauta Pharmacochemistry Award for Medicinal Chemistry and Chemical Biology ausgezeichnet. Yes: Then connect to the University network via VPN client in order to access the licensed contents. E-mail: christa.mueller@uni-bonn.de. Created by: | Chem. A research team of pharmacists at the University of Bonn has discovered two families of active substances that can block the replication of the SARS-CoV-2 coronavirus. PharmaCenter Bonn The Research Center for Innovative Drugs and Therapies at the University of Bonn is committed to interdisciplinary research and development projects . christa.mueller@uni-bonn.de. Christa MÜLLER | Cited by 1,655 | of University of Bonn, Bonn (Uni Bonn) | Read 150 publications | Contact Christa MÜLLER Renata Ciccarelli, Italy. The special thing about this type of drugs is that they only develop their effect when they are irradiated with light. 2 PharmaCenter Bonn, University of Bonn, Pharmaceutical Chemistry I, An der Immenburg 4, D-53121 Bonn, Germany. E-Mail: alexander.pfeifer[at]uni-bonn.de Prof. Dr. Christa E. Müller Speaker Pharmaceutical Institute, An der Immenburg 4, 53121 Bonn Phone (assistant Prof. Dr. Müller) +49 228 - 73-3890 E-Mail: christa.mueller[at]uni-bonn.de Dorothee Müssemeier Coordinator. Medical Chemistry, Chemical Biology and Molecular Pharmacology of Purinergic receptors (adenosine, P2Y, P2X, adenine receptors), G-protein-coupled receptors / orphan GPCRs, Synthesis of drug molecules (small molecules), Combinatorial synthesis, microwave-assisted synthesis, Molecular biological techniques (expression in mammalian cells, insect cells and yeast), mutagenesis studies, Development of radioligands (including PET-ligands), fluorescent ligands and ESR probes, NRW International Graduate Research School BIOTECH-PHARMA, Bonn International Graduate Research School of Drug Sciences, Copyright © Pharmazeutisches Institut. Showing 1 - 6 results of 6 for search 'Müller, Eva' Skip to content. Die Fachgruppe Pharmazie der Rheinischen Friedrich-Wilhelms-Universität Bonn wird durch die Fachgruppenvorsitzende Prof. Dr. Christa E. Müller vertreten. An der Immenburg 4. Hermes C, Richarz R, Wirtz DA, Patt J, Hanke W, Kehraus S, Voß JH, Küppers J, Ohbayashi T, Namasivayam V, Alenfelder J, Inoue A, Mergaert P, Gütschow M, Müller CE, Kostenis E, König GM, Crüsemann M. (2021) Thioesterase-mediated side chain transesterification generates potent Gq signaling inhibitor FR900359. Alzheimer's Disease, Collaboration with Dr. David Blum, Lille, France. Pharmacology of Purinergic Receptors (adenosine, P2Y, P2X, adenine receptors), G protein-coupled receptors / orphan GPCRs, Synthesis of drug molecules (small molecules), Combinatorial synthesis, microwave-assisted synthesis, Molecular biological techniques (expression in Department of Pharmaceutical & Medicinal Chemistry. Tel. Die Studie basiert auf Laborexperimenten. Copyright © Congress Chairperson: Christa E. Müller. Sang-Yong Lee 1 , Christa E Müller 1 Affiliation 1 PharmaCenter Bonn , Pharmaceutical Institute , Pharmaceutical Chemistry I , University of Bonn , An der Immenburg 4 , D-53121 Bonn , Germany . Weitere Informationen erhalten Sie bei den ERASMUS-Programmkoordinatoren/-innen: Fachl. Neurochallenges in Education & Research. Created by: No: You can then access licensed contents using the Service Pcs within the ULB Bonn. Ulrike Pag. Website Research Interests Medical Chemistry, Chemical Biology and Molecular Pharmacology of Purinergic Receptors (adenosine, P2Y, P2X, adenine receptors) G protein-coupled receptors / orphan GPCRs; Ectonucleotidase inhibitors; Development of screening assays Technologies / Resources … He acted for 10 years (2009 - 2019) as a member of the Strategic Advisory Board of the Neuroallianz consortium established by the PharmaCenter Bonn, which was substantially funded by the German Federal Ministry of Education and Research (BMBF). Tobias Claff and Dr. Christa Müller from the University of Bonn are looking at a glass sandwich plate on which the opioid receptor crystals form. Research Focus. ... Christa Müller. Pharmacist Prof. Christa Müller and neurologist Dr. Michael Wenzel work together in their project to develop a pharmacological approach that may in future be used to treat epilepsy patients. e-mail: purineclub@uni-bonn.de. « March 2021 » Are you a member of Bonn University? Im Profil von Christa Müller ist 1 Job angegeben. Principal Investigator: Christa Müller | ResearchGate, the professional network for scientists call: +49 228 732697. View ORCID Profile Christa E. Müller 2, † and ; View ORCID Profile Raymond C. Stevens 1, 7, † 1 iHuman Institute, ShanghaiTech University, Ren Building, 393 Middle Huaxia Rd, Pudong, Shanghai 201210, China. PharmaCenter Bonn. As in previous years, Bayer AG, in cooperation with the Pharma Centre Bonn and the Limes Institute, again awarded three prizes for 2018 for outstanding doctorates in the field of pharmaceutical research. Researchers discover SARS-CoV-2 inhibitors Uni Bonn CORONA stocks. Der P2Y 2-Rezeptor ist ein G-Protein-gekoppelter Rezeptor, der durch … Together with colleagues from Shanghai, Brussels, Canada and the USA, researchers from the University of Bonn have uncovered the binding mechanism of an important pain receptor. D-53121 Bonn . August 2020. Sehen Sie sich das Profil von Christa Müller im größten Business-Netzwerk der Welt an. As part of a university the PZB is especially dedicated to promote independent academic research in the field of pharmacological and pharmaceutical research . Pharmazeutisches Institut der Universität Bonn An der Immenburg 4 53121 Bonn . Quality Control and Assurance. Email: christa.mueller@uni-bonn.de. 2006, 13, 289-312 Molekulare Grundlagen der Aktivierung von P2Y-Rezeptoren. Markus Kuschak. Pharmaceutical Institute. Member, principal investigator (PI) of several projects), DFG-Forschergruppe FOR2372 (PI of Studienleistungen, Sprachkenntnisse, soziales Engagement, Motivation. Click on a logo to view the people involved from each partner institution. Email: christa.mueller(at)uni-bonn.de.